If you are looking for a quick method of skin rejuvenation that addresses concerns such as wrinkles, fine lines, and loss of skin elasticity, Ejal 40 and Profhilo may be the “magic wand”. But what is the difference between these two apart from the price and which one may be a better fit for your skin? In this guide, we provide some basic information on Ejal 40 and Profhilo treatments and a comparison chart to help you select a product for regaining your youthful appearance.
What Is Ejal 40?
Ejal 40 is a new generation of skin boosters that is based on highly purified medium molecular weight hyaluronic acid (1200-1800 кDa) and may be reasonably regarded as Profhilo’s up-and-coming younger sister. Despite many similarities between these two products, Ejal 40 is generally less expensive which may be an important point when deciding between them.
The power of Ejal 40 lies in its unique combination of bio-stimulation and bio-remodeling actions. Injected into 4 Bio Revitalization Points, Ejal 40 helps to eliminate wrinkles and restore a more youthful, rested appearance with uplifted contours through stimulating fibroblast activity and increasing the production of new collagen and elastin fibers. As a result, you can immediately notice significant improvements in skin quality, firmness, and tightness that may persist for up to 9 months.
What Is Profhilo?
Profhilo by IBSA Farmaceutici Italia S.r.l. is another hyaluronic acid-based skin booster that is aimed to restore your skin’s youthful appearance that should last for up to a year. Injected deeply into the dermis, IBSA’s patented combination of high and low molecular weight HA provides deep hydration to your skin while also stimulating the production of collagen and elastin, which results in long-lasting improvements in skin tone, radiance, and the appearance of fine lines.
Profhilo is administered using a newly developed BAP injection technique (5 Bio Aesthetic Points on each side of the face), making it the perfect treatment for those who want to achieve a fresher yet still natural appearance without downtime or severe side effects.
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Comparing Ejal 40 and Profhilo
| Ejal 40 | Profhilo | |
| Composition | Non-crosslinked high molecular weight HA (20 mg/ml) | Non-crosslinked high + low molecular weight HA (32 mg/ml) |
| Benefits | Restoring and strengthening the structure of extracellular matrix; Biorevitalizing dehydrated and sun-damaged skin; Restoring facial contours; Improving skin elasticity and firmness;Reducing the appearance of fine and deeper wrinkles; Enhancing skin plumpness and texture | Restoring and strengthening the structure of extracellular matrix; Biorevitalizing dehydrated and sun-damaged skin; Restoring facial contours; Improving skin elasticity and firmness; Reducing the appearance of fine and deeper wrinkles; Enhancing skin plumpness and texture |
| Duration of effects | 6-9 months | 6-12 months |
| Treatment areas | Face, neck, décolleté, and hands | Face, neck, décolleté, hands, and inner arms |
| Treatment protocol | A series of 3-5 treatments spaced one month apart | A series of 2-3 treatments spaced one month apart |
Expert Opinions
According to the article published on the website of National Institutes of Health, the goals of bio rejuvenation are “to increase the biosynthetic capacity of fibroblasts, inducing the reconstruction of an optimal physiologic environment; the enhancement of cell activity; hydration; and the synthesis of collagen, elastin, and HA.” Additionally, the PMFA journal published an article stating that “evidence shows the role of HA-based products in improving overall appearance and functionality of aged skin with a high safety profile and short downtime. Minimally invasive, it can be incorporated with more advanced or invasive treatments and is suitable for all ages.”
Conclusion: Making the Right Choice
In summary, while both Ejal 40 and Profhilo are hyaluronic acid-based treatments, they do have some distinct differences in their formulations, application, and results. The choice between Ejal 40 and Profhilo ultimately depends on your individual needs and skin concerns, making it a decision best left to a skilled injector. An experienced provider can assess your unique situation and develop a personalized treatment plan, potentially even recommending a combination of both fillers to achieve the desired outcome.
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